Evaluation of Immune Response against Leishmaniasis in BALB/c Mice Immunized with Cationic DOTAP/DOPE/CHOL Liposomes Containing Soluble Leishmania major Antigens

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Sphingomyelin Liposomes Containing Soluble Leishmania major antigens Induced Strong Th2 Immune Response in BALB/c Mice

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DDA/TDB liposomes containing soluble Leishmania major antigens induced a mixed Th1/Th2 immune response in BALB/c mice

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sphingomyelin liposomes containing soluble leishmania major antigens induced strong th2 immune response in balb/c mice

objective(s): soluble leishmania antigens (sla) provide suitable protection against leishmaniasis in murine model when delivered by an appropriate delivery system. liposomes have been shown to be suitable vaccine delivery systems against leishmaniasis, however, the phospholipase-a (pla) activity of sla is a drawback to prepare a stable liposomal sla. one strategy to overcome this problem might ...

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Sphingomyelin Liposomes Containing Soluble Leishmania major antigens Induced Strong Th2 Immune Response in BALB/c Mice

OBJECTIVE(S) Soluble Leishmania antigens (SLA) provide suitable protection against leishmaniasis in murine model when delivered by an appropriate delivery system. Liposomes have been shown to be suitable vaccine delivery systems against leishmaniasis, however, the phospholipase-A (PLA) activity of SLA is a drawback to prepare a stable liposomal SLA. One strategy to overcome this problem might b...

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ژورنال

عنوان ژورنال: Iranian Journal of Parasitology

سال: 2019

ISSN: 1735-7020

DOI: 10.18502/ijpa.v14i1.719